Diplomatic relations between the Republic of Belarus and the Republic of Uzbekistan were established on 21 January 1993. The Embassy of the Republic of Belarus in the Republic of Uzbekistan was opened in February 1994. In October 2017, was adopted the Resolution of the President of the Republic of Uzbekistan on the establishment of the Embassy of the Republic of Uzbekistan in the Republic of Belarus.
In 2016 the trade turnover with Uzbekistan amounted to 63.7 million dollars, exports – 35.9 million dollars.
In January–October 2017 the trade turnover between the Republic of Belarus and the Republic of Uzbekistan amounted to 97.4 million dollars, including the export of goods – 70.4 million dollars.
Belarus exports to Turkmenistan mainly polyacetals and polyethers, epoxy resins, medicines, tractors, petroleum products, non-electric household appliances for cooking, synthetic fibers, valves for pipelines, meters for the supply or production of gas, liquid and electricity, road and construction machinery, wallpapers and similar wall coverings.
The main import items from Uzbekistan are cotton fiber, cotton yarn, fresh and dried grapes, nuts and dried fruits, knitted fabrics and products.
In December 2017 in Minsk was held a meeting of the Joint Intergovernmental Commission on bilateral cooperation between the Republic of Belarus and the Republic of Uzbekistan. During the meeting parties discussed the issues of expanding in several areas the cooperation between Belarus and Uzbekistan.
In 2017 two assembly plants of Belarusian agricultural engineering were created on the territory of the Republic of Uzbekistan.